XEC: What we all know concerning the new covid-19 variant and its signs

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Covid-19 variant XEC could unfold extra simply than earlier variants

Jarun Ontakrai/Shutterstock

A brand new covid-19 variant referred to as XEC has began to unfold worldwide, primarily in Europe. Early proof signifies that it could transmit extra simply than previous variants, however public well being consultants say the brand new variant is similar to previous ones and the vaccines obtainable work towards it. Here’s what we find out about XEC thus far.

What’s the new covid-19 XEC variant?

XEC is a mixture of two different SARS-CoV-2 variants often known as KP.3.3 and KS.1.1. It shaped when the 2 variants contaminated the identical organism – equivalent to an animal or individual – concurrently, permitting them to share genetic materials.

XEC is a genetic offshoot of omicron, a extremely transmissible variant that first emerged in South Africa in 2021. “You may consider these new variants as great-grandchildren or grandchildren of omicron,” says William Schaffner at Vanderbilt College Medical Heart in Tennessee. This implies it shares most of the similar traits as different omicron subvariants, equivalent to spreading simply and inflicting much less extreme illness than the earliest SARS-CoV-2 strains.

When and the place was XEC recognized?

XEC was first recognized in August amongst covid-19 samples collected in Berlin two months earlier.

The earliest instances of the variant occurred in Italy in Could. Nevertheless, these samples weren’t uploaded to a world database that tracks SARS-CoV-2 variants, referred to as the World Initiative on Sharing All Influenza Knowledge (GSAID) till September.

What number of instances of XEC are there?

Knowledge from GSAID signifies that greater than 600 instances of XEC have been reported throughout 27 international locations, together with the UK, Germany, Canada and the US. Nevertheless, “not all international locations persistently report knowledge to GSAID, so the XEC variant is more likely to be current in additional international locations”, says Bhanu Bhatnagar on the World Well being Organisation (WHO) Regional Workplace for Europe.

The variant is prevalent in Europe, the place no less than 13 international locations have detected it, says Bhatnagar. To date, XEC constitutes about 8 per cent of all sequenced and reported samples from the continent this month, based on knowledge from GSAID. By comparability, it made up about 4 per cent of samples in August. Essentially the most generally sequenced variant in Europe remains to be KP.3.1.1 – additionally within the omicron household – at 48 per cent of all samples, says Bhatnagar.

XEC is most widespread in France, comprising roughly 21 per cent of sequenced covid-19 samples. It’s also gaining traction in Germany and the UK, the place it represents 15 per cent and eight per cent of sequenced samples, respectively, says Francois Balloux on the College Faculty London.

The brand new variant has additionally been detected within the US, the place it makes up roughly 1 per cent of instances, says Balloux. Nevertheless, XEC hasn’t appeared on the US Facilities for Illness Management and Prevention’s (CDC) covid-19 variant tracker, which incorporates variants as soon as they account for 1 per cent of all instances in per week.

What are the signs of XEC?

To date, XEC causes the identical signs as different covid-19 variants equivalent to fever, sore throat, cough and muscle aches and pains. “We can have our ears open to be taught whether or not there are likely some distinctive options, clinically,” says Schaffner. “We doubt it, however we’re at all times open to that.”

How harmful is XEC?

XEC doesn’t look like extra harmful or produce extra extreme illness than previous covid-19 variants, says Schaffner. The WHO hasn’t designated it as a variant of concern, both. That’s as a result of it shares most of the similar traits as different omicron subvariants, like inflicting extra delicate sickness than earlier strains, says Schaffner.

Is XEC extra transmissible?

It’s too early to say whether or not XEC is extra transmissible than different variants, says James Fielding on the WHO. Provided that it has gained a foothold amongst different circulating variants, nevertheless, it could have a bonus that makes it unfold extra simply.

As an example, a preliminary evaluation from Mike Honey, a knowledge specialist in Australia, means that XEC will change into the dominant variant in Europe and the UK in October. He predicts the identical will happen within the US and Canada later that month or in November.

“How broadly [spread] this explicit pressure will change into, I feel we simply have to attend and see,” says Schaffner.

Do covid-19 vaccines nonetheless work towards XEC?

The excellent news is that present covid-19 vaccines are anticipated to guard towards XEC, says Schaffner. It’s because up to date variations goal omicron subvariants.

The CDC recommends everybody 6 months or older obtain an up to date covid-19 booster in the event that they haven’t achieved so this yr. Within the UK, up to date vaccines can be found to folks 75 years and older, and people who stay in senior care services or have a weakened immune system.

In the end, Schaffner says there isn’t any motive to panic about XEC. “The virus is simply getting going, nevertheless it seems to be following the identical sample [as past ones]” he says. “My response is: usual, usual.”

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